Strategic Objectives
• Understand the biological mechanisms behind cellular arrest and survival.
• Identify how the SASP secretome triggers chronic systemic inflammation.
• Explore cutting-edge senolytic therapies to clear damaged cells.
• Learn lifestyle interventions to manage your internal signaling environment.
The Core Challenge
Lingering 'zombie cells' refuse to die, instead secreting a toxic inflammatory cocktail that poisons neighboring healthy tissue.
01
The Discovery of Senescence
02
The Anatomy of a Zombie Cell
03
The SASP Secretome
04
Guardians of the Genome
05
The Telomere Clock
06
The P16 Pathway
07
Inflammaging
08
Mitochondrial Dysfunction
09
The Epigenetic Landscape
10
Tumor Suppression vs. Aging
11
Senolytics: The First Wave
12
Quercetin and Dasatinib
13
Fisetin: Nature’s Senolytic
14
Senomorphics
15
Immune Surveillance
16
Senescence in Wound Healing
17
Organ-Specific Aging
18
The Role of Proteostasis
19
Autophagy: The Cleanup Mechanism
20
Future Frontiers
21