Strategic Objectives
• Master the principles of systemic biokinetics and biodistribution.
• Understand how nanoparticles navigate complex biological barriers.
• Identify the primary sites of accumulation and metabolic transformation.
• Discover the mechanisms behind nanomaterial excretion and long-term safety.
The Core Challenge
While cellular studies provide a glimpse, we lack a comprehensive understanding of how nanomaterials traverse the entire living organism.
01
The Nanoscale Frontier
02
The Biological Landscape
03
Entry Points
04
The Kinetic Equation
05
The Protein Corona
06
Navigating the Bloodstream
07
Crossing the Gatekeepers
08
Breaching the Brain
09
The Lymphatic Highway
10
Immune Recognition
11
Liver Accumulation
12
Splenic Filtration
13
Respiratory Uptake
14
Renal Clearance
15
Biliary Secretion
16
Intracellular Fate
17
Biotransformation
18
Long-term Persistence
19
Imaging the Invisible
20
Safety and Toxicology
21